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RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes

BACKGROUND: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence, if not the most important one, is the designing of tools that have minimal off-target effects (i.e. cleaves only the des...

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Autors principals: Lucier, Jean-François, Bergeron, Lucien Junior, Brière, Francis P, Ouellette, Rodney, Elela, Sherif Abou, Perreault, Jean-Pierre
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1634876/
https://ncbi.nlm.nih.gov/pubmed/17076887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-7-480
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