Intestinal elimination of ofloxacin enantiomers in the rat: evidence of a carrier-mediated process.
The aim of this work was to examine the mechanism involved in intestinal elimination of the two optical isomers of ofloxacin in the rat. An intestinal segment was isolated in situ and perfused with saline, while drug solution was administered via the carotid artery. Blood samples and intestinal effl...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163485/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878593/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2126 |
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