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Solubilization of Poorly Soluble PDT Agent, Meso-tetraphenylporphin, in Plain or Immunotargeted PEG-PE Micelles Results in Dramatically Improved Cancer Cell Killing in Vitro

Poorly soluble photodynamic therapy (PDT) agent, meso-tetratphenylporphine (TPP), was effectively solubilized using non-targeted and tumor-targeted polymeric micelles prepared of polyethylene glycol/phosphatidyl ethanolamine conjugate (PEG-PE). Encapsulation of TPP into PEG-PE-based micelles and imm...

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Detalhes bibliográficos
Main Authors: Roby, Aruna, Erdogan, Suna, Torchilin, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1634738/
https://ncbi.nlm.nih.gov/pubmed/16326084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejpb.2005.09.010
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