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Sequence analysis, purification, and study of inhibition by 4-quinolones of the DNA gyrase from Mycobacterium smegmatis.

We determined the nucleotide sequence of a 6-kb DNA region harboring the recF, orf192, gyrB, and gyrA genes from Mycobacterium smegmatis mc(2)155. The amino acid sequences deduced from gyrA and gyrB displayed 89 and 86% identity, respectively, with the DNA gyrase from Mycobacterium tuberculosis, and...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Revel-Viravau, V, Truong, Q C, Moreau, N, Jarlier, V, Sougakoff, W
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163472/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878580/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2054
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