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Inhibition of human cytomegalovirus immediate-early gene expression by an antisense oligonucleotide complementary to immediate-early RNA.

ISIS 2922 is a phosphorothioate oligonucleotide that is complementary to human cytomegalovirus (CMV) immediate-early (IE) RNA and that exhibits potent and specific antiviral activity against CMV in cell culture assays. Specific assay systems were developed to separately characterize the antisense an...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Anderson, K P, Fox, M C, Brown-Driver, V, Martin, M J, Azad, R F
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878571/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2004
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