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Semisynthetic echinocandins affect cell wall deposition of Pneumocystis carinii in vitro and in vivo.

Cyclic lipodepsipeptide compounds of the echinocandin class exhibit broad-spectrum antifungal activity and have been shown to be effective in the treatment of Pneumocystis carinii pneumonia in laboratory animal models. Previous studies have led investigators to propose that these compounds, active a...

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Published in:Antimicrob Agents Chemother
Main Authors: Bartlett, M S, Current, W L, Goheen, M P, Boylan, C J, Lee, C H, Shaw, M M, Queener, S F, Smith, J W
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163422/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843286/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1811
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