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Effects of roxithromycin and erythromycin on interleukin 8-induced neutrophil recruitment and goblet cell secretion in guinea pig tracheas.

Inhaled interleukin 8 caused an increase in goblet cell secretion in guinea pig tracheas, which was accompanied by mucosal infiltration of neutrophils. These responses were inhibited by pretreatment with roxithromycin or erythromycin in a dose-dependent fashion. Macrolides may thus be a value in pro...

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Détails bibliographiques
Auteurs principaux: Tamaoki, J, Nakata, J, Tagaya, E, Konno, K
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC163405/
https://ncbi.nlm.nih.gov/pubmed/8807072
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