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DNA Reshaping by MukB: RIGHT-HANDED KNOTTING, LEFT-HANDED SUPERCOILING
MukB is a bacterial SMC (structural maintenance of chromosome) protein required for faithful chromosome segregation in Escherichia coli. We report here that purified MukB introduces right-handed knots into DNA in the presence of type-2 topoisomerase, indicating that the protein promotes intramolecul...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1633270/ https://ncbi.nlm.nih.gov/pubmed/16368697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M504754200 |
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