Trophozoite elimination in a rat model of Pneumocystis carinii pneumonia by clinically achievable plasma deferoxamine concentrations.

In a rat model of Pneumocystis carinii pneumonia, a 3-week infusion of deferoxamine producing concentrations in plasma of > or = 1.5 micrograms m-1 eliminated the trophozoite life cycle stage. Since this concentration is well below that routinely achieved in patients treated for iron overload, defer...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Merali, S, Chin, K, Grady, R W, Clarkson, A B
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1996
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8723489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.5.1298
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