The Cys(4) zinc finger of bacteriophage T7 primase in sequence-specific single-stranded DNA recognition

Bacteriophage T7 DNA primase recognizes 5′-GTC-3′ in single-stranded DNA. The primase contains a single Cys(4) zinc-binding motif that is essential for recognition. Biochemical and mutagenic analyses suggest that the Cys(4) motif contacts cytosine of 5′-GTC-3′ and may also contribute to thymine reco...

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Hlavní autoři: Kusakabe, Takahiro, Hine, Anna V., Hyberts, Sven G., Richardson, Charles C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 1999
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC16326/
https://ncbi.nlm.nih.gov/pubmed/10200256
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