Population pharmacokinetic study of isepamicin with intensive care unit patients.

The pharmacokinetics (PK) of isepamicin, a new aminoglycoside, were studied in 85 intensive care unit (ICU) patients and were compared with those observed in 10 healthy volunteers. A parametric method based on a nonlinear mixed-effect model was used to assess population PK. Isepamicin was given intr...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Tod, M, Padoin, C, Minozzi, C, Cougnard, J, Petitjean, O
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163243/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8849264/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.4.983
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