Temporal variation in nephrotoxicity of low doses of isepamicin in rats.

The temporal variation in the nephrotoxicity of low doses of isepamicin was studied in male Sprague-Dawley rats treated with a single daily intraperitoneal injection of saline (NaCl, 0.9%) or isepamicin (80 mg/kg of body weight) at either 0800, 1400, 2000, or 0200 h for 4 and 10 days. On day 10, the...

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Bibliographic Details
Main Authors: Yoshiyama, Y, Grenier, L, Gourde, P, Simard, M, Lin, L, Morin, N J, Bergeron, M G, Labrecque, G, Beauchamp, D
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC163205/
https://ncbi.nlm.nih.gov/pubmed/8851618
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