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Temporal variation in nephrotoxicity of low doses of isepamicin in rats.

The temporal variation in the nephrotoxicity of low doses of isepamicin was studied in male Sprague-Dawley rats treated with a single daily intraperitoneal injection of saline (NaCl, 0.9%) or isepamicin (80 mg/kg of body weight) at either 0800, 1400, 2000, or 0200 h for 4 and 10 days. On day 10, the...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Yoshiyama, Y, Grenier, L, Gourde, P, Simard, M, Lin, L, Morin, N J, Bergeron, M G, Labrecque, G, Beauchamp, D
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851618/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.802
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