Luciferase in vivo expression technology: use of recombinant mycobacterial reporter strains to evaluate antimycobacterial activity in mice.

The development of new drugs and vaccines directed against Mycobacterium tuberculosis is severely impeded by the slow growth of this organism and the need to work under stringent biosafety conditions. These difficulties pose considerable obstacles when animal studies with M. tuberculosis are perform...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hickey, M J, Arain, T M, Shawar, R M, Humble, D J, Langhorne, M H, Morgenroth, J N, Stover, C K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.400
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