Luciferase in vivo expression technology: use of recombinant mycobacterial reporter strains to evaluate antimycobacterial activity in mice.

The development of new drugs and vaccines directed against Mycobacterium tuberculosis is severely impeded by the slow growth of this organism and the need to work under stringent biosafety conditions. These difficulties pose considerable obstacles when animal studies with M. tuberculosis are perform...

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Опубліковано в::	Antimicrob Agents Chemother
Автори:	Hickey, M J, Arain, T M, Shawar, R M, Humble, D J, Langhorne, M H, Morgenroth, J N, Stover, C K
Формат:	Artigo
Мова:	Inglês
Опубліковано:	American Society for Microbiology (ASM) 1996
Предмети:	Research Article
Онлайн доступ:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163123/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.400
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