Naphthalene sulfonate polymers with CD4-blocking and anti-human immunodeficiency virus type 1 activities.
PIC 024-4 and PRO 2000 are naphthalene sulfonate polymers that bind to CD4 with nanomolar affinity and block binding of gp120. Both have activity against human immunodeficiency virus type 1 in H9 cells, peripheral blood mononuclear cells, and primary monocyte/macrophages, are synergistic with zidovu...
Gorde:
| Argitaratua izan da: | Antimicrob Agents Chemother |
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| Egile Nagusiak: | , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology (ASM)
1996
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163090/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.234 |
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