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Protection and rescue from 2',3'-dideoxypyrimidine nucleoside analog toxicity by hemin in human bone marrow progenitor cells.

Long-term therapy of AIDS patients with 3'-azido-3'-deoxythymidine (AZT) remains of concern because of resulting hematopoietic toxicity. While the mechanism(s) of this toxicity remains elusive, alternative strategies are being developed to reduce these toxic effects, including combination therapy wi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Fowler, D A, Xie, M Y, Sommadossi, J P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163081/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.191
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