Preclinical pharmacokinetics and distribution to tissue of AG1343, an inhibitor of human immunodeficiency virus type 1 protease.

AG1343, a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) protease (Ki = 2 nM), was designed by protein structure-based drug design techniques. AG1343 has potent antiviral activity (95% effective dose = 0.04 microgram/ml) against a number of HIV-1 strains in acute and chronic models...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shetty, B V, Kosa, M B, Khalil, D A, Webber, S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1996
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC163067/
https://ncbi.nlm.nih.gov/pubmed/8787890
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