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Reversible Thermal Denaturation of a 60-kDa Genetically Engineered β-Sheet Polypeptide

A de novo 687-amino-acid residue polypeptide with a regular 32-amino-acid repeat sequence, (GA)(3)GY(GA)(3)GE(GA)(3)GH(GA)(3)GK, forms large β-sheet assemblages that exhibit remarkable folding properties and, as well, form fibrillar structures. This construct is an excellent tool to explore the deta...

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Bibliografske podrobnosti
Main Authors: Lednev, Igor K., Ermolenkov, Vladimir V., Higashiya, Seiichiro, Popova, Ludmila A., Topilina, Natalya I., Welch, John T.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630459/
https://ncbi.nlm.nih.gov/pubmed/16891363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.082792
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