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Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO(3)(−) secretion: relevance to cystic fibrosis

Fluid and HCO(3)(−) secretion are vital functions of the pancreatic duct and other secretory epithelia. CFTR and Cl(−)/HCO(3)(−) exchange activity at the luminal membrane are required for these functions. The molecular identity of the Cl(−)/HCO(3)(−) exchangers and their relationship with CFTR in de...

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Detalhes bibliográficos
Main Authors: Wang, Youxue, Soyombo, Abigail A, Shcheynikov, Nikolay, Zeng, Weizhong, Dorwart, Michael, Marino, Christopher R, Thomas, Philip J, Muallem, Shmuel
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630422/
https://ncbi.nlm.nih.gov/pubmed/17053783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601387
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