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Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X(7) receptor
P2X(7) receptors are ATP-gated cation channels; their activation in macrophage also leads to rapid opening of a membrane pore permeable to dyes such as ethidium, and to release of the pro-inflammatory cytokine, interleukin-1β (IL-1β). It has not been known what this dye-uptake path is, or whether it...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1630421/ https://ncbi.nlm.nih.gov/pubmed/17036048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601378 |
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