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Structure-activity and cross-resistance evaluations of a series of human immunodeficiency virus type-1-specific compounds related to oxathiin carboxanilide.

A series of compounds related to the nonnucleoside reverse transcriptase (RT) inhibitor (NNRTI) oxathiin carboxanilide (UC84) were evaluated for activity against the human immunodeficiency virus (HIV) to determine structural requirements for anti-HIV activity. Twenty-seven compounds representative o...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Buckheit, R W, Kinjerski, T L, Fliakas-Boltz, V, Russell, J D, Stup, T L, Pallansch, L A, Brouwer, W G, Dao, D C, Harrison, W A, Schultz, R J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163018/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593008/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2718
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