Inhibition of episomal hepatitis B virus DNA in vitro by 2,4-diamino-7- (2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-pyrrolo[2,3-d]pyrimidine.

The nucleoside analog 2,4-diamino-7-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)pyrrolo[2,3-d]pyrimidine (T70080) and several related compounds were evaluated for anti-hepatitis B virus (HBV) activity by using cultured 2.2.15 cells. T70080 reduced episomal viral replication in these cells by 50% at a...

Full description

Saved in:
Bibliographic Details
Main Authors: Ojwang, J O, Bhattacharya, B K, Marshall, H B, Korba, B E, Revankar, G R, Rando, R F
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC162987/
https://ncbi.nlm.nih.gov/pubmed/8585748
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items