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Efficacy of constant infusion of A-77003, an inhibitor of the human immunodeficiency virus type 1 (HIV-1) protease, in limiting acute HIV-1 infection in vitro.

A-77003, a human immunodeficiency virus type 1 (HIV-1) protease inhibitor, is effective for both acute and chronic infection in vitro and was evaluated clinically by continuous intravenous infusion administration. The minimum effective dose (the concentration required to completely inhibit viral rep...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Bilello, J A, Bilello, P A, Kort, J J, Dudley, M N, Leonard, J, Drusano, G L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8585738/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.11.2523
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