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Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine.

The nucleoside analog 2'-deoxy-2'-fluoroguanosine (2'-fluorodGuo) is phosphorylated by cellular enzymes and reversibly inhibits influenza virus replication in chick embryo cells within the first 4 h of infection. RNA hybridization studies revealed that primary and secondary transcription of influenz...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Tisdale, M, Ellis, M, Klumpp, K, Court, S, Ford, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1995
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162964/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8585725/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.11.2454
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