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Metabolic pathways for activation of the antiviral agent 9-(2-phosphonylmethoxyethyl)adenine in human lymphoid cells.

9-(2-Phosphonylmethoxyethyl)adenine (PMEA), the acyclic phosphonate analog of adenine monophosphate, is a promising antiviral drug with activity against herpesviruses, Epstein-Barr virus, and retroviruses, including the human immunodeficiency virus. In order to be active, it must be converted to the...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Robbins, B L, Greenhaw, J, Connelly, M C, Fridland, A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8619586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.10.2304
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