Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication.

HBY 097 [(S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3, 4-dihydroquinoxaline-2(1H)-thione] was selected from a series of quinoxalines as a nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (NNRTI). HBY 097 was shown to be a highly potent inhibit...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kleim, J P, Bender, R, Kirsch, R, Meichsner, C, Paessens, A, Rösner, M, Rübsamen-Waigmann, H, Kaiser, R, Wichers, M, Schneweis, K E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8619578/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.10.2253
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