Preclinical evaluation of HBY 097, a new nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 replication.

HBY 097 [(S)-4-isopropoxycarbonyl-6-methoxy-3-(methylthiomethyl)-3, 4-dihydroquinoxaline-2(1H)-thione] was selected from a series of quinoxalines as a nonnucleoside inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (NNRTI). HBY 097 was shown to be a highly potent inhibit...

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Detalhes bibliográficos
Main Authors: Kleim, J P, Bender, R, Kirsch, R, Meichsner, C, Paessens, A, Rösner, M, Rübsamen-Waigmann, H, Kaiser, R, Wichers, M, Schneweis, K E
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162925/
https://ncbi.nlm.nih.gov/pubmed/8619578
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