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The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus

Estrogen replacement therapy in women is associated with improvement of cognitive deficits and reduced incidence of Alzheimer's disease. The present study indicates that estrogen is neuroprotective against N-methyl-d-aspartate (NMDA)- and kainate-mediated neurotoxicity, an effect mediated by ty...

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Détails bibliographiques
Auteurs principaux: Bi, Ruifen, Broutman, Greg, Foy, Mike R., Thompson, Richard F., Baudry, Michel
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC16286/
https://ncbi.nlm.nih.gov/pubmed/10725383
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