The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampus

Estrogen replacement therapy in women is associated with improvement of cognitive deficits and reduced incidence of Alzheimer's disease. The present study indicates that estrogen is neuroprotective against N-methyl-d-aspartate (NMDA)- and kainate-mediated neurotoxicity, an effect mediated by tyrosin...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Bi, Ruifen, Broutman, Greg, Foy, Mike R., Thompson, Richard F., Baudry, Michel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2000
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16286/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10725383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.060034497
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