Mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine against herpesviruses.

The activity, metabolism, and mode of action of (R)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine (H2G) against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) and varicella-zoster virus (VZV) were studied. Compared to acyclovir (ACV), H2G has superior activity against VZV (50% inhibitory conce...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Lowe, D M, Alderton, W K, Ellis, M R, Parmar, V, Miller, W H, Roberts, G B, Fyfe, J A, Gaillard, R, Ertl, P, Snowden, W
Formato: Artigo
Idioma:Inglês
Publicado: 1995
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC162829/
https://ncbi.nlm.nih.gov/pubmed/7486922
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares