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Characterization of fluoroquinolone-resistant mutant strains of Mycobacterium tuberculosis selected in the laboratory and isolated from patients.

To examine the mechanism of resistance to fluoroquinolones in Mycobacterium tuberculosis, we selected spontaneous fluoroquinolone-resistant mutants from a susceptible strain, H37Rv, and studied the susceptibilities of these mutants and two fluoroquinolone-resistant clinical isolates (A-382, A-564) t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Alangaden, G J, Manavathu, E K, Vakulenko, S B, Zvonok, N M, Lerner, S A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162811/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7486904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.8.1700
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