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Mechanism of action of antimycobacterial activity of the new benzoxazinorifamycin KRM-1648.

The mechanism of antimicrobial activity of KRM-1648 (KRM), a new rifamycin derivative with potent antimycobacterial activity, was studied. Both KRM and rifampin (RMP) inhibited RNA polymerases from Escherichia coli and Mycobacterium avium at low concentrations: the 50% inhibitory concentrations (IC5...

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Bibliografiska uppgifter
Huvudupphovsmän: Fujii, K, Saito, H, Tomioka, H, Mae, T, Hosoe, K
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC162768/
https://ncbi.nlm.nih.gov/pubmed/7492091
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