Point mutation in the pribnow box, the molecular basis of beta-lactamase overproduction in Klebsiella oxytoca.
Klebsiella oxytoca mutants resistant to a variety of beta-lactams were obtained in vitro on aztreonam. Constitutive beta-lactamase production was much higher in the mutants than in the susceptible strains (75-fold). The only difference observed in these mutants compared with the susceptible strains...
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| 發表在: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
1995
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162743/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1365 |
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