Interactions of biapenem with active-site serine and metallo-beta-lactamases.

Biapenem, formerly LJC 10,627 or L-627, a carbapenem antibiotic, was studied in its interactions with 12 beta-lactamases belonging to the four molecular classes proposed by R. P. Ambler (Philos. Trans. R. Soc. Lond. Biol. Sci. 289:321-331, 1980). Kinetic parameters were determined. Biapenem was read...

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Publicat a:	Antimicrob Agents Chemother
Autors principals:	Felici, A, Perilli, M, Segatore, B, Franceschini, N, Setacci, D, Oratore, A, Stefani, S, Galleni, M, Amicosante, G
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1995
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7574520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.6.1300
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