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Activities of the triazole SCH 51048 against Coccidioides immitis in vitro and in vivo.

The activity of the novel triazole SCH 51048 was tested against Coccidioides immitis. SCH 51048 inhibited C. immitis in vitro; MICs for 13 isolates ranged from < or = 0.39 to 0.78 micrograms/ml, and minimum fungicidal concentrations ranged from < or = 0.39 to 1.6 micrograms/ml. In vivo, no mice trea...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Clemons, K V, Homola, M E, Stevens, D A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162703/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7625808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.5.1169
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