Activities of the triazole SCH 51048 against Coccidioides immitis in vitro and in vivo.

The activity of the novel triazole SCH 51048 was tested against Coccidioides immitis. SCH 51048 inhibited C. immitis in vitro; MICs for 13 isolates ranged from < or = 0.39 to 0.78 micrograms/ml, and minimum fungicidal concentrations ranged from < or = 0.39 to 1.6 micrograms/ml. In vivo, no mice trea...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Clemons, K V, Homola, M E, Stevens, D A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1995
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162703/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7625808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.5.1169
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