Fluconazole penetration in cerebral parenchyma in humans at steady state.

We studied fluconazole penetration in the brain in five patients who had a deep cerebral tumor whose removal required the excision of healthy brain tissue. Plasma and brain samples were simultaneously obtained after oral ingestion of 400 mg of fluconazole daily for 4 days (90% of steady state). Fluc...

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Bibliografiske detaljer
Main Authors: Thaler, F, Bernard, B, Tod, M, Jedynak, C P, Petitjean, O, Derome, P, Loirat, P
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162699/
https://ncbi.nlm.nih.gov/pubmed/7625804
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