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Toll-Like Receptors on Hematopoietic Progenitor Cells Stimulate Innate Immune System Replenishment

Toll-like receptors (TLRs) are best known for their ability to recognize microbial or viral components and initiate innate immune responses. We showed here that TLRs and their co-receptors were expressed by multipotential hematopoietic stem cells, whose cell cycle entry was triggered by TLR ligation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nagai, Yoshinori, Garrett, Karla P., Ohta, Shoichiro, Bahrun, Uleng, Kouro, Taku, Akira, Shizuo, Takatsu, Kiyoshi, Kincade, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1626529/
https://ncbi.nlm.nih.gov/pubmed/16782035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2006.04.008
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