(R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine is a potent inhibitor of feline immunodeficiency virus infection.

The antiviral efficacy of acyclic nucleoside phosphonates, including 9-(2-phosphonylmethoxyethyl)adenine (PMEA) and (R)-9-(2-phosphonylmethoxypropyl)-2,6-diaminopurine [(R)-PMPDAP] against feline immunodeficiency virus (FIV) infection was determined. (R)-PMPDAP showed the highest selectivity index (...

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Bibliographic Details
Main Authors: Vahlenkamp, T W, De Ronde, A, Balzarini, J, Naesens, L, De Clercq, E, van Eijk, M J, Horzinek, M C, Egberink, H F
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC162616/
https://ncbi.nlm.nih.gov/pubmed/7793884
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