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Microglia: a cellular vehicle for CNS gene therapy
Metachromatic leukodystrophy (MLD) is a lysosomal storage disease caused by deficiency of the enzyme arylsulfatase A (ARSA). MLD is characterized by progressive demyelination and neurological deficits. Treatment of MLD is still a challenge due to the fact that the blood-brain barrier is a major obst...
Uloženo v:
| Hlavní autor: | |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Clinical Investigation
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1626126/ https://ncbi.nlm.nih.gov/pubmed/17080190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30230 |
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