Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis
The neu (c-erbB-2, Her-2) protooncogene is amplified and overexpressed in 20–30% of human breast cancers. Although transgenic mouse models have illustrated the role of Neu in the induction of mammary tumors, Neu expression in these models is driven by a strong viral promoter of questionable relevanc...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16259/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10716706/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050408497 |
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