Identification of the aminocatechol A-3253 as an in vitro poison of DNA topoisomerase I from Candida albicans.
The aminocatechol A-3253 is active against several pathogenic fungi, including Candida albicans, Cryptococcus albidus, and Aspergillus niger. A-3253 interferes with both the in vitro biosynthesis of (1,3)-beta-glucan and the activity of topoisomerases I isolated from Candida spp. It is likely that o...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1995
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162588/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7793856/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.39.3.586 |
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