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CP-115,953 stimulates cytokine production by lymphocytes.

The cytotoxic quinolone CP-115,953 specifically exerts its inhibitory effect upon eukaryotic topoisomerase II. CP-115,953 stimulates DNA cleavage mediated by topoisomerase II with a potency approximately 600 times greater than that of ciprofloxacin, a quinolone antibacterial agent that currently is...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Riesbeck, K, Forsgren, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.476
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