CP-115,953 stimulates cytokine production by lymphocytes.

The cytotoxic quinolone CP-115,953 specifically exerts its inhibitory effect upon eukaryotic topoisomerase II. CP-115,953 stimulates DNA cleavage mediated by topoisomerase II with a potency approximately 600 times greater than that of ciprofloxacin, a quinolone antibacterial agent that currently is...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Riesbeck, K, Forsgren, A
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7726518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.2.476
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