Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system

Recombinant adeno-associated virus vectors based on serotype 2 (rAAV2) can direct transgene expression in the central nervous system (CNS), but it is not known how other rAAV serotypes perform as CNS gene transfer vectors. Serotypes 4 and 5 are distinct from rAAV2 and from each other in their capsid...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Davidson, Beverly L., Stein, Colleen S., Heth, Jason A., Martins, Inês, Kotin, Robert M., Derksen, Todd A., Zabner, Joseph, Ghodsi, Abdi, Chiorini, John A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050581197
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