Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor

Proteolipid protein (PLP)-139–151 is the dominant encephalitogenic peptide that induces experimental autoimmune encephalomyelitis (EAE) in SJL (H-2(s)) mice. To examine the contribution of T cell receptor (TCR) specificity in the induction of EAE, we generated transgenic mice expressing the rearrang...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Waldner, Hanspeter, Whitters, Matthew J., Sobel, Raymond A., Collins, Mary, Kuchroo, Vijay K.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2000
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16253/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737797/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.7.3412
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