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Cloning, sequencing, and site-directed mutagenesis of beta-lactamase gene from Streptomyces fradiae Y59.

The beta-lactamase gene from Streptomyces fradiae Y59 was cloned and sequenced. To determine which amino acid residues are critical in binding activity to blue dextran, chimera beta-lactamases were constructed and their binding abilities were determined. The results suggested that blue dextran bindi...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Kurai, S, Urabe, H, Ogawara, H
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1995
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.1.260
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