Loading...

Effect of pyrimido[1,6-a]benzimidazoles, quinolones, and Ca2+ on the DNA gyrase-mediated cleavage reaction.

The quinolones inhibit the A subunit of DNA gyrase in the presence of Mg2+ by interrupting the DNA breakage and resealing steps, and the latter step is also retarded without quinolones if Mg2+ is replaced by Ca2+. Pyrimido[1,6-a]benzimidazoles have been found to represent a new class of potent DNA g...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Gmünder, H, Kuratli, K, Keck, W
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC162503/
https://ncbi.nlm.nih.gov/pubmed/7695300
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!