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Selection and characterization of RNA aptamers to the RNA-dependent RNA polymerase from foot-and-mouth disease virus

Foot-and-mouth disease virus causes a highly contagious disease of agricultural livestock and is of enormous economic importance. Replication of the RNA genome of the virus, via negative strand intermediates, involves an RNA-dependent RNA polymerase (3Dpol). RNA aptamers specific to this enzyme have...

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Autores principales: Ellingham, Mark, Bunka, David H.J., Rowlands, David J., Stonehouse, Nicola J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1624902/
https://ncbi.nlm.nih.gov/pubmed/17018573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.161006
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